Chloroform metabolismus
WebChloroform: a review of its metabolism, teratogenic, mutagenic, and carcinogenic potential. Chloroform: a review of its metabolism, teratogenic, mutagenic, and carcinogenic … WebMetabolismus a fyziologické působení [ editovat editovat zdroj] Methanol se metabolizuje především v játrech, a to pomocí enzymu alkoholdehydrogenázy na formaldehyd. Ten se dále přeměňuje (pomocí aldehyddehydrogenázy a dalších enzymů) na kyselinu mravenčí.
Chloroform metabolismus
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WebMar 1, 2003 · Chloroform oxidation was poorly dependent on pO2, whereas the reductive metabolism was highly inhibited by O2. The production of dichloromethyl radical was … WebJ. Estévez, E. Vilanova, in Encyclopedia of Toxicology (Third Edition), 2014 Toxicokinetics. Chloroform is well absorbed, metabolized, and eliminated by mammals after oral, …
WebAn in vitro investigation of the reductive metabolism of chloroform. In hypoxic (1% pO2) and anoxic (0% pO2) incubations of CHCl3 with rat liver microsomes from PB-induced … WebApr 7, 2024 · chloroform (CHCl3), also called trichloromethane, nonflammable, clear, colourless liquid that is denser than water and has a pleasant etherlike odour. It was first …
WebBeim Mischen von Kokain und Kalziumkarbonat „täuscht“ die Wechselwirkung das Gehirn dazu, größere Mengen entweder des Kokains, des Kalziumkarbonats oder beider gleichzeitig zu sich zu nehmen. Das Gehirn entwickelt anscheinend eine größere Toleranz für beide Drogen, was die Benutzer dazu veranlasst, mehr zu konsumieren. WebOct 15, 1999 · Chloroform is a nongenotoxic-cytotoxic liver and kidney carcinogen and nasal toxicant in some strains and sexes of rodents. Substantial evidence indicates that …
WebChloroform (CHCl 3) is a colorless liquid that quickly evaporates into gas. It can harm the eyes, skin, liver, kidneys, and nervous system. Chloroform can be toxic if inhaled or swallowed. Exposure to chloroform may also …
WebStudy with Quizlet and memorize flashcards containing terms like C1 - C4 účinek, C5-C7 účinek (3), C8-C12 vlastnosti and more. apx700 yamaha guitarWebwww.ncbi.nlm.nih.gov apx-7 ct yamaha guitarChloroform is metabolized in the liver by the cytochrome P-450 enzymes, by oxidation to chloromethanol and by reduction to the dichloromethyl free radical. Other metabolites of chloroform include hydrochloric acid and digluathionyl dithiocarbonate, with carbon dioxide as the predominant end … See more Chloroform, or trichloromethane (often abbreviated as TCM), is an organic compound with the formula CHCl3 and a common organic solvent. It is a very volatile, colorless, strong-smelling, dense liquid produced on … See more The molecule adopts a tetrahedral molecular geometry with C3v symmetry. The chloroform molecule can be viewed as a See more Chloroform was synthesized independently by several investigators circa 1831: • Moldenhawer, a German pharmacist from Frankfurt an der Oder, … See more In terms of scale, the most important reaction of chloroform is with hydrogen fluoride to give monochlorodifluoromethane CHCl3 + 2HF → CHClF2 + 2 HCl The reaction is … See more The total global flux of chloroform through the environment is approximately 660000 tonnes per year, and about 90% of emissions are natural in origin. Many kinds of seaweed produce chloroform, and fungi are believed to produce chloroform in soil. Abiotic processes … See more Industrially, chloroform is produced by heating a mixture of chlorine and either methyl chloride (CH3Cl) or methane (CH4). At 400–500 °C, a free radical halogenation occurs, converting … See more Exposure Chloroform is known to form as a by-product of water chlorination, along with a range of other disinfection by-products, and as such is … See more apx600 yamaha priceWebMar 1, 2003 · The role of human CYP2E1 in CHCl 3 metabolism at low levels, typical of actual human exposure, provides insight into the molecular basis for eventual difference in susceptibility to chloroform-induced effects due to either genetic, pathophysiological, or environmental factors. Footnotes apxah goat fur rugWebIndustrially, chloroform is produced by heating a mixture of chlorine and either methyl chloride (CH 3 Cl) or methane (CH 4 ). [10] At 400–500 °C, a free radical halogenation occurs, converting these precursors to progressively more chlorinated compounds: CH 4 + Cl 2 → CH 3 Cl + HCl CH 3 Cl + Cl 2 → CH 2 Cl 2 + HCl CH 2 Cl 2 + Cl 2 → CHCl 3 + HCl apx adapterWebChloroform metabolism can occur in liver, under physiological pO 2 conditions, with and without participation of O 2. Although, under anaerobic conditions the protein covalent binding of CHCl 3 metabolites is lowered, cytochrome P-450 decrease is more substantial. apx600 yamaha guitarWebChloroform MSDS Section 1: Chemical Product and Company Identification Product Name: Chloroform Catalog Codes: SLC1888, SLC5044 CAS#: 67-66-3 RTECS: FS9100000 TSCA: TSCA 8(b) inventory: Chloroform CI#: Not available. Synonym: Trichloromethane; Methane, trichlor-Chemical Name: Chloroform apx 700 nt yamaha