WebAcute Toxicity – Skin Corrosion –irreversible Serious eye damage - produces Contact by skin or ingestion damage to skin after up to 4 irreversible eye tissue damage in produces adverse effects within hrs of contact the eye within 21 of contact 24 hrs , or 4 hrs by inhalation Skin Irritation –reversible Eye Irritation - production of WebThe rule’s preamble describes substances with a high degree of acute toxicity as those substances that are “fatal or cause damage to target organs as a result of a single …
Chapter 6: SKIN CORROSION/IRRITATION DEFINITIONS …
WebFeb 16, 2024 · Acute toxicity describes the adverse effects resulting from a single exposure to a substance. Under Paragraph A.1.1. of Appendix A to to 29 CFR 1910.1200, the OSHA Hazard Communication Standard (HCS 2012), acute toxicity is defined specifically as adverse effects occurring following oral or dermal administration of a … Webapplied independently. The criteria for classification of a substance in acute categories I to III are defined on the basis of the acute toxicity data only (EC 50 or LC 50). The criteria for classification of a substance into chronic categories combine two types of information, i.e. acute toxicity data and environmental fate data manheim township police
SOP: Acutely Toxic Chemicals PennEHRS - University …
Webthe animals. When observations are made of dermal irritation/corrosion in acute toxicity studies and are observed up through the limit dose, additional testing would not be needed, provided that the dilutions used and species tested are equivalent. In vitro alternatives that have been validated and Web4.1.1.2.1 The basic elements for use within the harmonized system are: (a) acute aquatic toxicity; (b) potential for or actual bioaccumulation; (c) degradation (biotic or abiotic) for organic chemicals; and (d) chronic aquatic toxicity. 4.1.1.2.2 While data from internationally harmonized test methods are preferred, in practice, data from WebAcute Toxicity - Inhalation Skin Corrosion & Irritation Serious Eye Damage & Eye Irritation Some hazard classes (e.g. flammables, oxidizers, carcinogens) follow a GHS hierarchy for hazard statements and signal … korean with ina book