WebCurrently, the lab is working on photoswitches belonging to several different families including spiropyran, naphthopyran, and hemithioindigo. Based on innovation in signal transduction and functional materials, new nanoscale sensing interfaces are being developed to quantify various ions , gas , nucleic acids , and proteins . Web27 jan. 2024 · Background: Hemithioindigo is a promising molecular photoswitch that has only recently been applied as a photoswitchable pharmacophore for control over bioactivity in cellulo. Uniquely, in contrast to other photoswitches that have been applied to biology, the pseudosymmetric hemithioindigo scaffold has allowed the creation of both dark-active …
Prohlížení dle vedoucího práce "Roithová, Jana" Digitální …
Web27 jan. 2024 · Hemithioindigo is a promising molecular photoswitch that has only recently been applied as a photoswitchable pharmacophore for control over bioactivity in cellulo. Uniquely, in contrast to other photoswitches that have been applied to biology, the pseudosymmetric hemithioindigo scaffold has allowed the creation of both dark-active … Web22 okt. 2024 · Herein we report on the synthesis of a hemithioindigo molecular motor bearing thioether feet for surface attachment on its thioindigo fragment. We also give a full theoretical description of its ground state energy profile together with an experimental evaluation of the visible light driven unidirectional rotation in solution. homely meaning uk
Hemithioindigos for Cellular Photopharmacology: Desymmetrised …
Web24 feb. 2024 · We present a simple hemithioindigo photoswitch that can efficiently be photoisomerized using green and red light while maintaining a high thermal barrier of the metastable state. This highly sought after properties allow for selective switching in a mixture of hemithioindigo dyes. Web27 jul. 2024 · Pyrrole Hemithioindigo Antimitotics with Near‐Quantitative Bidirectional Photoswitching that Photocontrol Cellular Microtubule Dynamics with Single‐Cell … Web26 mrt. 2024 · Hemithioindigo-based molecular motors are powered by nondamaging visible light and provide very fast directional rotations at ambient conditions. Their … hindi short film youtube